2009 Volume Two

نویسندگان

  • Jennifer Carroll
  • Jenna Arruda
  • Jianbiao Pan
  • Michael Krist
  • Andrew Farris
چکیده

The purpose of this research project is to identify and chemically profile active extracts of a marine sponge, Clathria sp., collected from St. Thomas, US Virgin Islands. Previously, pteridine alkaloids, sterol sulfates, and bromine-containing amides collected from various species of Clathria have shown anti-microbial and anti-cancer activities [1]. Sponge extracts were isolated through a combination of liquid-liquid extractions, adsorption silica-gel column chromatography and high-pressure liquid chromatography (HPLC). These extracts were tested for cy­ totoxicity and antifouling properties through an Artemia sp. lethality test and

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تاریخ انتشار 2009